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Topamax (Topiramate)

Topamax is an anticonvulsant drug used to treat epilepsy in both children and adults. In children it is also indicated for treatment of Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). It is also Food and Drug Administration (FDA) approved, and now most frequently prescribed for, the prevention of migraines. It has been used by psychiatrists to treat bipolar disorder, although it is not FDA approved for this purpose and such use is somewhat controversial. This drug has been investigated for use in treatment of obesity, especially to aid in the reduction of binge eating, and also as a possible treatment for alcoholism.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Oral status among seniors in nine nursing homes in Styria, Austria. Dark-field microscopy is achievable in the operating room and can quantify MPI from the colonic serosa in different colonic lesions. To date, there are few reports of paroxysmal exercise-induced dystonia associated with familial epilepsy. Inferolateral pontine infarcts are well-described lesions of the anterior inferior cerebellar artery territory with a wide variety of clinical presentations.

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The randomized controlled trials included a total of 126 participants with traumatic brain injury and 62 care-givers and suggest a positive influence of peer support for traumatic brain injury survivors and their caregivers in areas of social support, coping, behavioural control and physical quality of life. The elasticity factor has the predominant effect, compared with the chemical and topographical factors, on cell adhesions of human mesenchymal stem cells (hMSCs).

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Trace proteinuria could be a useful indicator of microalbuminuria in the general population, and especially in subjects at high risk of cardiovascular disease. The severe GTP depletion associated with neurological deficits may mirror the situation in the brain, which like the erythrocyte is largely dependent on salvage to sustain its GTP levels.

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The locomotor activity depressed by reserpine, spiroperidol, and pimozide was elevated by ergometrine. Their potential as in situ forming biomaterials has rendered these hydrogels very attractive. After infection of the PBMC with HIV, the culture fluid was checked for infectivity (TCID50) and the level of p24 antigen. These updates on the ascidian model, which complement other lower chordates and vertebrates, shed light on the evolutionary origin of the pituitary primordium. The addition of hydroxyl radical scavengers such as mannitol did not affect the formation of DMPO-OH, but the signal turned faint in the presence of EDTA.

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The findings from this study provide experimental evidence for the involvement of N-glycosylation in tissue regeneration and cell signaling. We study the above transitions and the elasticity of the smectic-C and biaxial phases in three different but related models: Landau-like phenomenological models as functions of the Cauchy-Saint-Laurent strain tensor for both the biaxial and the smectic-C phases and a detailed model, including contributions from the elastic network, smectic layer compression, and smectic-C tilt for the smectic-C phase as a function of both strain and the c-director. This limits the possible encounter trajectories for these particles to relatively circular, prograde orbits. Selective amide bond replacement with metastable ester bonds is a preferred approach to the preparation of peptides with biophysical properties that otherwise inhibit synthesis.

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There were 28 J-shaped pouches and 13 S-shaped pouches in this group. High-dose sotalol is safe and effective in neonates and infants with refractory supraventricular tachyarrhythmias. She was treated with a diuretic, a beta adrenergic blocker and an angiotension enzyme inhibitor. We found that miR-331-3p expression in GBM cell lines is significantly lower than in normal brain, and that transient overexpression of miR-331-3p inhibits GBM cell line proliferation and clonogenic growth, suggesting a possible tumor suppressor role for miR-331-3p in this system. Some peculiar immunohistochemical findings were obvious, as well as a lack of continuity of the tumor with the local lacrimal gland.

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The GL service source code is free and open source software, distributed under the GNU Lesser General Public License (LGPL) version 3 or later. Retinal targets for calmodulin include proteins implicated in synaptic transmission. HSV is injected into the area of interest, and after several days, the animals are perfused and processed for immunohistochemistry with antibodies to HSV proteins. prostaglandin E1 but the latter agent induces significantly more pain.

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Viral CC motif chemokine 2 binds to a broad spectrum of viral and human chemokine receptors of all 4 classes and, depending on the receptor, acts either as an agonist or an antagonist, inducing or blocking the recruitment of specific immune cell subsets. Further studies are warranted to establish the potential factors that might lead to the observed differences across populations. We also highlight the significance of the Hippo pathway activator RASSF1A tumor suppressor, a direct target of ataxia telangiectasia mutated and ataxia telangiectasia and Rad3 related ATR. The Mg(II) complexes displayed even higher quantum yields than the corresponding Zn-complexes.

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Chromatographic characteristics of these stationary phases were evaluated by variation of experimental conditions for a set of diverse analytes with neutral, acidic, basic and zwitterionic character revealing the presence of multimodal retention capabilities (i.e. The aa substitutions detected mainly occurred in VPI and antigenic changes were detected in late isolates both at antigenic site 1, resulting in loss of binding of Mab 4GO7, and at a closely located site which has not yet been named, recognized by Mab C29. New developments in proteinuria assessment have included the use of spot urinary microalbumin to creatinine ratio measurements.

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We distributed an anonymous survey to 473 radiation oncologists and residents. Recent evidence has also indicated that Abeta-induced synaptic defects and memory impairment could be explained by a loss of both AMPA and NMDA receptors through endocytosis. Employing an H3 driven pharmacodynamic model, the series was then further optimised through to a lead compound that showed robust in vivo functional activity and possessed overall excellent developability properties. Development of a nuclear morphometric signature for prostate cancer risk in negative biopsies.

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In order to quantify differences across strains, innervation territories of thoracic dorsal cutaneous nerves were mapped and measured in adult mice. The observation that individual monoclonal antibodies react with sets of related proteins is discussed. Basilar arterio-venous pseudoparallelism due to persistence of embryonal venous pattern.

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Platelet impairment of the ADP pathway is associated with increased sensitivity to t-PA. Major health organizations have identified this issue as an urgent health problem for women, but the effects of these campaigns have rarely been tested with the target audience most affected by the issue.

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The detection of human pseudotuberculosis cases in Volyn Province from 1975 to 1989 Multidrug resistance has classically been described as a cell membrane phenomenon. Thyroid carcinoma with extensive tumor thrombus in the superior vena cava: A case report. The nuclear interaction of bcl-xL and cdk1(cdc2) suggests that bcl-xL is coupled to the stabilization of a cell-cycle checkpoint induced by DNA damage, and this effect is genetically distinct from its function on apoptosis. Influence of rapeseed oil feeding on morphology and oxidative properties of mitochondria isolated from the rat heart

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The methodological aspects of biological experiments in space as the main source of reliable information on the biological role of gravity are discussed. Thus, the aim of sport and exercise appears to differ among ages in the maintenance of bone health in females. Randomly selected sample of 1360 adult residents of the township of Nambour who completed a food frequency questionnaire in 1992 and were monitored for BCC and SCC until 31 December 2002.

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The aim of this review is to summarize available data, discuss the information gained from these publications, and put this information into perspective with more recent developments of lung function testing in both infants and older children with CF. Magnetic force generated by the gradient coils of an MRI system provides a propulsion mechanism that simplifies miniaturization and bypasses energetic challenges. A macro language allows for fully automated and database-controlled large-scale data analysis. These data suggest that the localization of ATF-2 in cortical neurons in AD may reflect early pathological changes characteristic of AD, and that these histochemistrical methods may allow one to differentiate between healthy and mildly damaged neurons. Diabetes mellitus and venous thromboembolism: A systematic review and meta-analysis.

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In this study, based on the concept that protein complexes with similar topology may have similar functions, we firstly model protein complexes as weighted graphs with nodes representing the proteins and edges indicating interaction between proteins. Time course experiments indicate that the latter is a modification derivative of the 14-kD peptide after the removal of the transit peptide.

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We present a rare case of an ulcerated ileocecal valve lipoma presenting as lower gastrointestinal bleeding that was treated successfully with laparoscopic resection. The notices include modifications for the purpose of clarity, timeliness, and correctness, as of August 19, 1983. tournefortii was first crossed with the three basic diploid species, B.

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Whereas the full-length TA isoforms of p63 and p73 can activate downstream target genes and induce apoptosis, the DeltaN isoforms which lack the transactivation domain can act as dominant inhibitors of the full-length forms of p53, p63 and p73, inhibiting transactivation of target genes and induction of apoptosis. The optimum goal for the diastolic blood pressure remains at 80 to 85 mm Hg. We evaluated the effectiveness of coaching on improving type 2 diabetes goals after 3 years of implementation in primary care. An unusual effect of application of the amino acid L-arginine on cat visual cortical cells.

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Although the mechanism of this glucose intolerance and hypertension is not completely understood, a role for the renin-angiotensin system (RAS) has been proposed. We also studied susceptibility of RPN2-suppressed ESCC cells to docetaxel. Further studies with results of treatment outcomes in this community are needed.

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Participants were randomly allocated to perform matched-bias (MB) or unmatched-bias (UB) exercises first, in 2 crossover groups. Stroke (mean 3.65, CI 3.58-3.73) was also associated with the greatest reduction in positive well-being whereas diabetes (mean 3.81, CI 3.76-3.86) and cancer were least affected (3.85, CI 3.79-3.91), compared with no illness (mean 3.97, CI 3.95-4.00).

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These results show that proton minibeam radiation therapy results in reduced adverse effects compared with conventional homogeneous broad-beam irradiation and, therefore, might have the potential to decrease the incidence of side effects resulting from clinical proton and/or heavy ion therapy. Ground-state analysis of ordered superstructures in the basal plane of YBa2Cu

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A.A., an inhibitor of liver PH-FU hydrolase, had no antitumor activity but greatly enhanced the activity of PH-FU when coadministered. jegathesan in Culex quinquefasciatus (Diptera: Culicidae) resistant to single or multiple toxins of Bacillus thuringiensis subsp. The compression syndrome was reproduced in rats aged one month and the efficacy of phytin in correcting the activity infringement and restoring the content of basic components of the hepatocyte monooxygenase enzyme system was studied in the postcompression period.

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To determine the time trend of HIV infection among non-professional blood donors at the Christian Medical College and Hospital, Vellore, the annual HIV prevalence among them for the years 1993-1997 was compared with that of the previous 5 yr. Thus, taken together these results indicate that the development of the human IgE response in allergic SCID mice can be modulated by modified allergen and a Th1 cytokine.

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Office hypertension in type 2 (non-insulin-dependent) diabetic patients. The team also conducted a review of administrative law intended to control OOP payments and IPs. The spindle cells had fibroblastic features with pale eosinophilic cytoplasmic extensions and inconspicuous nucleoli. Hence, the possibility that untreated microsporidium infection can lead to perforation cannot be ruled out.

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Administration of intravenous immunoglobulin and milrinone, a phosphodiesterase inhibitor, has been shown to modulate inflammation, to reduce sympathetic overactivity, and to improve survival in patients with EV71 autonomic nervous system dysregulation and pulmonary edema. These vectors allow manipulations in prototrophic yeast strains with expression of two gene cassettes per plasmid, and will be particularly useful for metabolic engineering applications. Anomalous magnetic moment of electron and constraint on composite weak-interaction bosons. We directly compared results in patients undergoing slings with and without augmentation. A link between monoamine oxidase-A and apoptosis in serum deprived human SH-SY5Y neuroblastoma cells.

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GM1-SCO and SAL-SAL (but not SAL-SCO) mice spent significantly less time in the aversive enclosed arm of the discriminative avoidance apparatus when compared to the time spent in the non-aversive enclosed arm. The culture supernatant is potent, avid and specific as demonstrated by its reactivity with a large sample of donor bloods tested manually and on the Olympus PK 7100 automated blood grouping machine. In contrast, dynorphin A-(1-6), -(1-5) and -(6-17) did not disrupt hindlimb motor function with or without peptidase inhibition. pneumoniae RTIs and climatic conditions is not well documented in the literature. There were no significant correlations between the z scores of temporal correlation coefficients of the 6 pairs of ROIs in patients and age of seizure onset, duration of epilepsy, number of medications, seizure frequency, and IQ.

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This systematic review focuses on controlled clinical trials evaluating the effect of pharmacist intervention on medication errors (MEs) in ICU settings. Intra-arterial injections of latex rubber were performed in 12 cadaver limbs. The importance of investigating thoroughly before classifying patients who report rarely with neuritic symptoms without any evidence of skin lesion is stressed.

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In-vitro and in-vivo study of amorphous spironolactone prepared by adsorption method using supercritical CO2. This study was conducted to determine the effect of massage therapy on stress in nurses. Our data also demonstrate the feasibility of using menthol PK in children with IBS to support definitive studies of PMO dose-effect relationships. Skin melanoma should also be considered with some caution, due to variability among registries in coding in situ cases.

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Role of excitatory amino acid neurotransmission in synaptic plasticity and pathology. SD rats were subjected to 4 weeks of CUS to induce depressive-like behaviors. All blood investigations for etiology of recurrent DVT were normal except for serum homocysteine level, which was mildly increased. Cognitive and combination intervention subjects were statistically younger than behavioral and attention-control subjects.

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The k2 value did not change in patients investigated twice, although there was a considerable decrease in renal function. The gating effect also generalizes to other thin-film materials, suggesting that these phenomena could provide optical control of chemical potential in a wide range of ultrathin electronic systems. In this article we provide an in-depth review of the complex pathophysiological mechanisms linking OSA to T2DM. The design also provided improved access for plating superior and inferior to its shaft while it was engaged. These should receive bilateral imaging studies and a metabolic bone workup in order to define the status of the fracture and determine the appropriate management before considering any other surgical intervention.

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Decentralized, departmental library collections, in health care systems. In a previous study of the effect of age on information processing, both age and stimulus complexity slowed reaction time (RT) and the latency of the P300 component of the brain event-related potential (ERP). Characterization of the host inflammatory response following implantation of prolapse mesh in rhesus macaque.

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In this environment, movement is critical to escape from disturbances and to find resources scattered in space and time. Actinic keratosis is one of the most common dermatological diagnoses worldwide, especially among the elderly, fair-skinned, and immunocompromised, and is associated with a risk of transformation to skin cancer. Immunohistochemical studies revealed polyclonal kappa- and lambda-light chains in the proliferation of plasma cells. A significant reduction in MMP-2 expression and an increase in E-cadherin expression in sCLU-knockdown HCCLM3 cells were observed, as well as a significant increase in MMP-2 expression and a decrease in E-cadherin expression in HepG2 cells overexpressing sCLU.

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Interventricular delay in severe aortic stenosis recognized by gated radionuclear blood pool scanning. Moreover, the surface-immobilized enzyme exhibited resistance against its inhibitor due to the occupation of an inhibitor binding site on the enzyme.

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Declining Trends and Widening Disparities in Overweight and Obesity Prevalence Among Massachusetts Public School Districts, 2009-2014. The inflammation of the meninges was only reflected by an increase in S-IL-2R in cerebrospinal fluid (CSF) in 1/14 patients with aseptic meningitis and 3/10 patients with purulent meningitis. socially anxious individuals after hearing negative affective-laden sounds: an experimental investigation.

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In this paper, the features, motility, and frictional force of the small intestine are analyzed for determining the design strategy. A twin study of structural chromosome aberrations in lymphocytes. On beryllium lymphocyte transformation test and beryllium levels in work environment.

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A battery of in vitro recombinant yeast bioassays incorporated with exogenous metabolic activation system (rat liver preparation, S9 mix) was conducted to assess the estrogen receptor (ER), androgen receptor (AR), progesterone receptor (PR), and thyroid receptor (TR) ant/agonistic activities of effluents collected from Datansha WWTP. Bowel function recovered 4 days postoperatively and gradually resumed ordinary diet. Prospective validation of a surgical complications grading system in a cohort of 2114 patients.

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Despite the emerging evidence regarding pharmacological activities of cannabinoids, their effective introduction into clinical therapy still remains controversial and strongly limited by their unavoidable psychotropicity. Effect of treatment with botulinum toxin on neurogenic blepharospasm.

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We propose that this is a consequence of failing to target the right molecular pathway in the most relevant patient group at the appropriate time and place in disease progression. The standalone aminopeptidase PepN catalyzes trazodone overdose death images the maturation of blasticidin S from leucylblasticidin S.

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The product of the 1.1 mM transition in 175-base-pair nucleosomes is elongated into a more asymmetric particle. The patient is presently in good health and has been disease-free for five years and nine months. Hydrops of the gallbladder: unusual roentgenographic demonstration. mebendazole tablets in india Prevalence of the use of antihypertensive medications in Greenland: a study of quality of care amongst patients treated with antihypertensive drugs.

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The increase in fetal hemoglobin (HbF) in response to hydroxyurea (HU) varies among patients with sickle cell anemia. Recently, positron emission tomography has begun to identify brain regions that appear to be uniquely activated in this condition. Effects of desmopressin for the treatment of nocturnal polyuria in elderly women: impact on related sleep quality. People receiving HF achieved superior housing outcomes and showed more rapid improvements in community robitet medication interaction functioning and quality of life than those receiving treatment as usual.

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Flavonoids and Auxin Transport Inhibitors Rescue Symbiotic Nodulation in the Medicago truncatula Cytokinin Perception Mutant cre1. The correlation between the specific area at the tenth closure and the age of the acyclovir bula ampola syndrome children prompt us to consider two different trends in neuroblastomas, those which invariably lead to death and whose grade of differentiation bears no correlation with the outcome, and those which undergo spontaneous or treatment-induced regression, and whose maturity has a linear relationship with the age of the child at diagnosis.

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Studies conducted by optometric students can provide a major contribution. Fewer cytomegalovirus complications after kidney transplantation by de novo use of mTOR inhibitors in comparison to withdrawal symptoms of escitalopram mycophenolic acid.

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Female rat castration leads to enhancement of FSH and LH activity of the hypophysis. We report a case of NPPE induced by direct suctioning of the endotracheal tube adapter during thoracic sympathetic ganglionectomy without recognized upper airway obstruction. To our ketazol shampoo and conditioner knowledge, the overall characteristics and specific determinants of pretest risk of psychosis onset in individuals undergoing clinical high risk (CHR) assessment are unknown.

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Distinct pathways involved in sound recognition and localization: augmentin antibiotic dosage duration a human fMRI study. From a human placental lambda gt11 cDNA library, we have isolated a cDNA clone that encodes the entire 215-residue amino acid sequence of HMG-1.

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Although based on a limited sample size, our study indicates that Xpert MTB/RIF is a useful method for the diagnosis of cervical TB lymphadenitis in HIV-infected patients, regardless of the bacillary load in paroxetine weight gain cause smear-positive samples or the CD4 T cell count. Diagnosis of human papillomavirus infection in paraffin-embedded cervical tissues by gene clip technology Four-dimensional heteronuclear triple-resonance NMR spectroscopy of interleukin-1 beta in solution.

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Phagolysosomal alterations induced by unleaded gasoline in epithelial cells of the proximal convoluted tubules of male rats: effect of esopral 40 mg posologia amoxicilina dose and treatment duration. Unexpectedly, the sponge metagenomes were dominated by a ubiquitously present, evolutionarily distinct, and highly sponge-specific group of polyketide synthases (PKSs). Thirty five subjects with both parents in the top third of their age specific blood pressure distributions and 31 subjects with both parents in the bottom third of their blood pressure distributions restricted their intake of sodium for eight weeks while taking part in a double blind, randomised crossover trial of supplements of sodium and placebo. It briefly reviews the history of chiropteran viruses and discusses their emergence in the context of geography, phylogeny, and ecology.

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Natural products are a rich source of bioactive nexium esomeprazol 20 mg compounds, and numerous natural compounds have found application in cancer chemotherapy. Teratoma-like lesions of the placenta are rare and of disputed histogenesis.

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Structures of the recently solved HIN domains reveal that these domains exhibit either absent in melanoma2 (Aim2) HIN-like or p202 HINa-like modes of DNA binding. The new nursing associate role takes nurses further away from patient care, the reason generic azelastine people choose nursing.

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Spinal cord injury patients who had NDO, on clean intermittent self-catheterisation, and were refractory to oral amoval 500 mg to g medications, were recruited. The main pathological findings include infection, debris granulomas, chronic non-specific inflammatory changes, PVNS. The serum m-parathyroid hormone levels showed no significant changes. Overall, this work illustrates how shifting chemical signals can tune actomyosin network behaviour during development.