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Human anti-nuclear ribonucleoprotein antigen autoimmune sera contain a novel subset of autoantibodies that stabilizes the molecular interaction of U1RNP-C protein with the Sm core proteins. Nine major intermediates were identified in two stages of the aggregation process. Claude Bernard-Horner syndrome after puncture of the internal jugular vein

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The results clearly indicate that the homologous recombination through the short direct repeated sequence is the main cause of the varied deletions found in the genomes of M2 subclones. Estrogenic and cytotoxic potentials of compounds isolated from Millettia macrophylla Benth. Causes of discomfort in the academic workplace and their associations with the different burnout types: a mixed-methodology study. The process looked like flattening of mucosal folds or slight map-like elevation of antral and pyloric mucosa.

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However, no data on the entomologic aspects of malaria transmission have been published from Zambia in more than 25 years. Sensitive diagnostic assays using nucleic acid amplification and hybridization techniques have been commercialized and will allow standardization of CMV diagnostics in antiviral drug trials. Acceptability of HEWs was often low due to a perceived lack of sensitivity of HEWs and concerns about medicines given at the health post.

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Alteration of protein synthesis and induction of specific protein phosphorylation by hyperthermia. k-Top Scoring Pairs (k-TSP) algorithm and significance analysis of microarrays (SAM) were applied to obtain comprehensive panels of PD-predictive biomarkers. An Open Trial of Electronic Cigarettes for Smoking Cessation Among Methadone-Maintained Smokers.

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(3) Each result should be quantitatively validated using more than one assay. Magnetic resonance imaging showed acute infarction in the right middle cerebral artery (MCA). Oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells give rise to oligodendrocytes and type-2 astrocytes in cultures of rat optic nerve.

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The increased viral growth rate is thought to increase the infectivity of the secondary infectious class. Healthcare providers treating postpartum women with complicating mental health conditions should be cognizant of the potential ramifications on maternal functioning.

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A Bioenergetics Approach to Understanding the Population Consequences of Disturbance: Elephant Seals as a Model System. In our evaluation of 193 pitchers examined during their preseason physical examinations, we identified a statistically significant association between decreased total arc of motion, decreased shoulder strength, and GIRD. This is the root cause for the well-known grand challenge of semantic interoperability in healthcare: data exchange and analysis of medical information systems has major limitations. To understand how RNA libraries can evolve from randomness toward highly active catalysts, we analyze the original samples that led to the discovery of Diels-Alderase ribozymes by next-generation sequencing.

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Hematopoietic cell transplantation for Chediak-Higashi syndrome. In this article the techniques of clinical neurological evaluation are discussed. Genetic control of susceptibility to group A streptococcal infection in mice.

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Ultrasound-induced cavitation has been widely used for delivering DNA vectors into cells. Legacy Making Through Illness Blogs: Online Spaces for Young Adults Approaching the End-of-Life. Activities of antioxidant enzymes in muscle, liver and lung of chickens with inherited muscular dystrophy. The 4-year trend in the total number of Graduate Medical Education filled positions has been relatively consistent, with some recent increases in primary care residency positions, especially in Family Medicine and Medicine/Pediatrics.

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Results indicate that phosphatidylcholines and phosphatidylethanolamines levels change more than other phospholipids and that increases of unsaturated fatty acids occurred at the expense of linoleic and linolenic acids. We searched PubMed and Google Scholar to identify papers that investigated associations between genetic variants and CRC risk and published through 25 December 2012.

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Chronic restraint stress in rats causes sustained increase in urinary corticosterone excretion without affecting cerebral or systemic oxidatively generated DNA/RNA damage. The calculated ZFS parameters are in good agreement with high-field, high-frequency electron paramagnetic resonance spectroscopy and frequency domain magnetic resonance spectroscopy data. The staining pattern with the individual probes disclosed variable developmental regulation. The suprachiasmatic nucleus (SCN) of the hypothalamus controls circadian rhythmicity in mammals (for reviews, see Refs. Such a partially active state is assumed by a truncated form of the murine urokinase-type plasminogen activator (muPA), consisting of residues 16-243.

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These work measures, along with the written examination, were administered to a sample of 128 entry-level practitioners drawn from 10 test sites throughout the country. In contrast, the extent of this interaction in pH 7.4 phosphate buffer was less than that in distilled water because the common ion effect and high concentration of sodium ion retarded the hydration of SA and the binding of calcium ions with carboxyl groups of SA. It is thereby illustrated that the use of advanced solvent potentials can provide higher accuracy compared to various simpler approaches for the prediction of solvent shifts and do so in a computationally competitive manner. Impaired endothelial regulation of vascular tone in patients with systemic arterial hypertension. Gregarines observed under light microscopy in intestinal extracts of house dust mites (Dermatophagoides spp.) are described for the first time in scientific literature.

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The expression of CARMA1 may be involved with pathogenesis and progression of ABC-like DLBCL. Thus, the phenylene motion that can consistently be observed in NMR and neutron scattering experiments is sensitive to the local packing. However, increased functional activity of these and other PKC isoforms leads to reversal in paclitaxel resistance. Comparison of a Hartree, a Hartree-Fock, and an exact treatment of quantum-dot helium. We sought to characterize the practice of issuing do-not-resuscitate orders in intracerebral hemorrhage.

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The study also documents an extended list of 140 process-related performance indicators in a systematic manner by further categorizing them into 11 performance perspectives in order to gain a holistic view. The aim of the therapeutic trials was to optimize the treatment of severe aplastic anemia (SAA) and moderate aplastic anemia in children who lack a suitable bone marrow donor, using immunosuppressive therapy in the most effective combination and dose. These results show that our method will be of broad use throughout the field of metabolic engineering. Factors that can invalidate the findings of a crossover trial include nonuniform pharmacologic and psychologic carry-over effects, failure to return patients to their baseline state before the crossover, nonuniform changes in the patients over time, and the use of time-dependent response measures.

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This study demonstrated that the expression of Girdin in invasive breast cancer is strongly associated with lymph node metastasis. For this reason, the National Medical Association and the National Hispanic Medical Association issued a joint consensus statement recommending African Americans consume three to four servings of low-fat dairy every day.

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Depression is by far the most common such disorder, and the suicide rate is alarmingly high. These results suggest the possibility that intra-tumoral LATS2 mRNA levels may be clinically useful for the prediction of response to EC treatment by breast cancer patients. The cell cycle parameters of most of the specimen were measured within 24 h of sampling.

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Effectiveness was defined in terms of the ability to correctly detect the presence or absence of disease. To the best of our knowledge multiple cutaneous nerve abscesses involving the entire subcutaneous plexus on a TT patch is a very uncommon observation.

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Null alleles of hid recapitulate the antiapoptotic activities of Ras/MAPK, providing genetic evidence that downregulation of hid is an important mechanism by which Ras promotes survival. We find that the oxidation-number sum rule is valid in many situations, although exceptions occur for each material studied, most notably when exposed to small oxidative ligands.

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To correlate changes in uridine transport and colony morphology with differentiation of human breast cancer cells by tamoxifen and related agents. An assessment of the clastogenic potential of 4-chloromethylbiphenyl in human lymphocytes in vitro. Patients were well tolerated, and this regimen is a new choice in treatment of relapse/refractory MM.

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Proteins of the LIM family are critical regulators of development and differentiation in various cell types. Pharmacokinetic evaluation of C-3 modified 1,8-naphthyridine-3-carboxamide derivatives with potent anticancer activity: lead finding. On the basis of the results with exquisite morphological growth patterns and the increase in the amount of tempelate DNA prepared from the cultured cells, it is evident that the cells of M.leprae are capable of multiplication under cell-free in vitro conditions.

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The cremaster muscle (CM) has been considered to participate in regulation of blood flow and temperature of the testis. The effect of various factors on morbidity of manic-depressive psychoses and the features of its course (a clinico-statistical study) TEWL was measured at baseline and after the 5th, 10th, 15th and 20th tape-strips.

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Haptoglobin phenotype may alter endothelial progenitor cell cluster formation in cerebral small vessel disease. Although no human cases of infection have been reported since 1984, infected urban rats have been found throughout Japan, and infected grey red-backed voles (Clethrionomys rufocanus) have been identified in Hokkaido. This article summarizes our experience with neuroendoscopy, highlighting the salient challenges and outcome. The O,N-deacylated derivative (deON) and polysaccharide part (PS) from the lipopolysaccharide (LPS) of Escherichia coli C strain were separated by strongly basic anion-exchange chromatography (SAX) based on the differences in the number of charged phosphate and ethanolamine substituents. We selected eligible articles independently and in duplicate and extracted data in duplicate.

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Sudan III was not detected in the receptor phase regardless of the presence of enhancer. Aspergillus ulcerative tracheobronchitis is a life-threatening form of invasive aspergillosis and is seldom seen in patients without underlying an immunocompromised state.

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Effect of ionol-type antioxidants on the energetics of liver mitochondria However, without the electrical ground on the body, we could detect the heartbeat signal, a land of the motion artifacts by the variation of the blood vessel volume. vivax (and malaria in general) in Peru include logistical difficulties in accessing remote riverine populations, consequences of government policy and poverty trends, and obtaining international funding for malaria control and elimination. Germ-line mosaicism simulates genetic heterogeneity in Wiskott-Aldrich syndrome. In the present study, FGF21was administrated in high-fat diet-induced obese mice and tunicamycin-induced 3T3-L1 adipocytes, and metabolic parameters, endoplasmic reticulum (ER) stress indicators, and insulin signaling molecular were assessed by Western blotting.

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Use of case studies to introduce undergraduate students to principles of food microbiology, molecular biology, and epidemiology of food-borne disease. In the Iraqi medical education environment where the need for triage is immediate, but the ability to stage practice is nearly impossible, blending didactic learning with simulation-based triage offers an alternative training methodology. Here we studied whether stability and sensitivity are affected by the connectivity structure in recurrently connected spiking networks. To assess the relative roles of body fat, body perception, and body ideals as motivations for dieting in college women. Evaluation of risk factors of retinopathy of prematurity genesis, ocular errors, and psychomotoric development in prematurely born children in West Bohemia--twelve years longitudinal study

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KIF23 encodes mitotic kinesin-like protein 1, which plays a critical role in cytokinesis, whereas the cellular role of the proteins encoded by CDAN1 and SEC23B is still unknown. The distribution and characteristics of LDL receptor mutations in China: A systematic review.

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The authors conclude with a summary of recommendations for positive partnering between occupational therapy and organizations that serve persons with disabling conditions. A regression analysis revealed that serum ferritin and transferrin receptor levels were significantly associated with a decrease in total and uncarboxylated osteocalcin. This article investigates the deficiency in sample size determinations for precise interval estimation of interaction effects that can result from ignoring the stochastic nature of continuous predictor and moderator variables in MMR. The actions of this topogenic sequence were independent of on-going translation and could be conferred to heterologous proteins by the engineering of a discrete set of codons.

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Functional magnetic resonance imaging during pantomiming tool-use gestures. Intracellular parasites, by contrast, are resistant to PDTC killing, although treatment does cause reversible growth arrest. Attentional bias for prescription opioid cues among opioid dependent chronic pain patients. Thrombosis of splanchnic blood vessels is one of the most difficult complications and most frequent causes of death in patients with myeloproliferative disorders. We analyzed the ability of buprenorphine to prevent the effects of experimental surgery on HPA activation (plasma corticosterone levels), NK activity and lung diffusion of the NK sensitive tumor MADB106.

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The phenyl rings in the most active herbicidal DPP derivatives either are unsubstituted or bear fluorine atoms. Transcriptional components of anteroposterior positional information during zebrafish fin regeneration. Seventy-eight dogs admitted to intensive care units at University of Tennessee (UT) and Colorado State University (CSU). Insufficiency fracture of the sacrum revealing a pregnancy associated osteoporosis. The best-known property of superfluid helium is the vanishing viscosity that objects experience while moving through the liquid with speeds below the so-called critical Landau velocity.

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Most immunotherapeutic studies are designed to exploit the capacity of dendritic cells for inducing cell-mediated effects as well as immune memory responses for destroying residual tumor cells and preventing recurrence. Study 1 compared conversational behaviors of high-lonely and low-lonely college students during brief heterosexual interactions. However, better functional results can be expected in dorsal nail plate. ZIC2 and RASGRF1 are susceptibility genes, not only for common myopia, but also for high myopia. These results suggest that functional limitations are more important than pain for adult deformity patients when deciding for operative or nonoperative treatment.

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The O2 release rates were deduced from the CO2 absorption rates multiplied by 32/44. The objective of this study was to determine the accuracy of ultrasonographic measurement of amniochorionic membrane thickness (AMT) in the prediction of preterm birth among an asymptomatic pregnant population. Individuals with Williams syndrome, a rare genetic disorder, are characterized by specific medical, cognitive, and behavioral phenotypes and often have high anxiety levels as well as phobia. The goals of this study were to investigate to what degree intra-individual changes in DNA methylation are associated with aging during childhood and dissect the methylation changes directly associated with aging from the effect mediated through variation in cell-type composition (CTC).

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A promising approach for improving the recovery of heart transplants. QoL was measured using the Short-Form Health Survey(SF-36) and alleviation of symptoms was documented using an outcome tool (PAS score), based on visual analog scales, preoperatively, postoperatively and at 6 months. Enhancing Anger Perception With Transcranial Alternating Current Stimulation Induced Gamma Oscillations. Topical pimecrolimus and tacrolimus transiently induce neuropeptide release and mast cell degranulation in murine skin.

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It is evident that a maldistribution of nursing personnel exists. The residual primary tumor demonstrated continued regression during chemotherapy, and magnetic resonance imaging of the spine and cytopathological examination of the cerebrospinal fluid showed no evidence for other sites of metastatic tumor. However, the mechanisms underlying gene and genome evolution in Oryza polyploids remain largely unknown.