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Can verapamil induce second response in patients refractory to vincristine? Practical issues related to uterine pathology: in situ and invasive cervical glandular lesions and their benign mimics: emphasis on cytology-histology correlation and interpretive pitfalls. Interestingly, zileuton blocked ONOO--induced nitrotyrosination of recombinant 5-LO in a cell-free system as well as of native enzyme in intact cells. None of the patients died within 3 months, and 3 patients were re-admitted (2 for suspicion of DVT, which was not found, and 1 for joint mobilization). Various vesicle structures and lipid compositions have been studied to identify the optimal type of liposome for delivery of the macrophage-activating agent muramyl dipeptide (MDP) to macrophages.

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Reference change values and determinants of variability of NT-proANP and GDF15 in stable chronic heart failure. Because the complete process is anhydrous, it can be easily extended to produce sustained release formulations of other hydrophilic drugs. Dynamin 2 expression as a biomarker in grading of cervical intraepithelial neoplasia.

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Downregulation of an astrocyte-derived inflammatory protein, S100B, reduces vascular inflammatory responses in brains persistently infected with Borna disease virus. The kinetic parameters determined from the progress curves proved very close to those obtained by the initial rate analysis. nematophila with arachidonic acid did not show any significant inhibition of hemocyte phagocytosis.

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Re-irradiation doses ranged from 16 to 25 Gray (Gy) delivered by robotic arm stereotactic irradiation in 2-5 fractions. In summary, we further elucidate phenotypical changes induced by in vitro culture of hBMSCs, highlight interindividual differences in the phenotype of these cells and for the first time show the intracellular expression of CD34.

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Danish nurses report a supportive nurse work environment with overall scores at the same level as Magnet hospitals. Serotonin, a major player in the regulation of feeding and affect. The spectrograms of serotonin eliminated from the blood of patients are different by forms and may serve as one of the tests for the establishment of the degree of the disorder.

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Novel AI-2 quorum sensing inhibitors in Vibrio harveyi identified through structure-based virtual screening. Universal vaccination would also decrease the numbers of symptomatic infection, hospitalization, and QALYs lost, but would increase 51 deaths due to hepatitis A, and 1507, 1929 more RMB Yuan for each QALY gained from the health system and societal respectively, in the regions with highest infection rate. Nitrogen loss, as determined by a nitrogen mass balance, increased with elevated CO2 levels in the shoot environment and with a high NO3- concentration in the rooting zone.

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Thr bronchial artery did not accompany the intrapulmonary part of the primary bronchus. The optical isomers of the Glu residue are an essential determinant of the EW dipeptide biological activity. Cross-reactive immune response induced by the Vi capsular polysaccharide typhoid vaccine against Salmonella Paratyphi strains. Creation of the bony Bankart led to a significant increase in total range of motion and anterior-inferior translation compared to the intact shoulder. Schwann cells are main effectors for regeneration in a variety of peripheral neuropathic conditions, including inherited, inflammatory, toxic, and diabetic neuropathies, as well as traumatic injuries to peripheral nerve fibers.

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A thorough knowledge of the various pitfalls and pseudolesions that may be encountered at CT colonography, along with use of dedicated problem-solving techniques, will help the radiologist differentiate between definite colonic lesions and pseudolesions. Metal-Free Radical Haloazidation of Benzene-Tethered 1,7-Enynes Leading to Polyfunctionalized 3,4-Dihydroquinolin-2(1H)-ones. Breast-conserving therapy in patients with an inherited susceptibility to breast cancer.

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Proceedings of the International Symposium on Nonhuman Primate Research in Space, Moscow, Russia, June 22-26, 1998. A second group of patients had received retrobulbar block at the hospital. The effect of recombinant human growth hormone therapy in patients with completed stroke: a pilot trial. However, accessing particular -1 PRF stimulator information represents a bottle-neck in combating the emerging epidemic viral pathogens such as Middle East respiratory syndrome coronavirus (MERS-CoV).

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Microsomal metabolism of the carcinogen, N-2-fluorenyl-acetamide, by the mammary gland and liver of female rats. We further developed multiple efficient and scalable techniques to visualize multi-set intersections and the corresponding intersection statistics. To review recent findings from memory research and related scientific studies and to provide an overview of their implications for clinical practice. Recombinational hotspot specific to female meiosis in the mouse major histocompatibility complex. The influence of angiography table shields and height on patient and angiographer irradiation during interventional radiology procedures.

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Antidepressants, neuroleptics, and beta-blockers were prescribed most frequently. This observation suggests that ODC and CK-II, enzymes with different catalytic purposes, crosstalk within the colonic crypt continuum. Our real-time ab initio simulation found logarithmic temperature dependence of the Auger rates in semiconductor quantum dots (QDs), which agrees well with the recent experimental observations. Second primary cancers in breast cancer patients in Vaud, Switzerland.

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Gene therapy in simple terms can be defined as a medical treatment that exerts its effects using molecules of DNA or RNA within cells. There is a need for further research to investigate the impact of hypertension and LVH on HRT. The diabetic environment is highly complex and the interplay of various diseases makes this an extremely challenging condition to manage. Manual small-incision cataract surgery is almost as effective, but less expensive. Cumulative (Dis)Advantage and the Matthew Effect in Life-Course Analysis.

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Hemodynamic indices and LV segmental contractility were assessed. Pharmacogenetics: implications of race and ethnicity on defining genetic profiles for personalized medicine. It has been calculated that if rhodopsin molecules are associated in photoreceptor membranes they have such a high diamagnetic susceptibility anisotropy that it manifests itself macroscopically in the magnetic field in the order of magnitude of 0.1 kG (8 .

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The subfraction compositions of the histone F1 of several tissues from the chicken, pigeon, and titmouse have been compared. Splenectomy in patients suffering from onco-haematological conditions presents clotting-related problems which make correct haemostasis more difficult. Aim of the study is the analysis of surgical morbidity in cervical lymphadenectomy for thyroid cancer.

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Trends in stroke survival incidence rates in older Australians in the new millennium and forecasts into the future. Association between circulating soluble receptor for advanced glycation end products and atherosclerosis: observations from the Dallas Heart Study. The sessions were audiotaped and transcribed verbatim, and transcripts were coded using a combination of deductive and inductive methods. While people only represent one real world, they are likely to have representations for multiple fictional worlds. The activation duration and function of leg muscles, especially the knee extensor muscle, are significantly affected by the speed of the selected Tai Chi Chuan movement.

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A 21-year-old man developed a swollen eyelid and painful monocular visual loss of his left eye which did not improve after treatment by intravenous steroid and albendazole. Saltmarsh vegetation, seston and microphytobenthos are all conspicuous components of most temperate estuaries and they potentially contribute to the estuarine food chain. Renal artery aneurysms constitute one per cent of all aneurysms. Alternative chemotherapeutic agents should be considered for metastatic PGL resistant to conventional therapy.

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They differentiate in the thymus, where interactions with thymus-resident antigen-presenting cells, an instructive cytokine milieu, and stimulation of the T cell receptor lead to the selection into the Treg lineage and the induction of Foxp3 gene expression. In all eukaryotic cells, vesicular trafficking is crucial for maintaining cellular and organelle functions. Despite immediate antibiotic therapy a multiple organ failure developed, with ARDS, cardiac failure, disseminated intravascular coagulation and acute renal failure. Classification of lung cancer patients and controls by chromatography of modified nucleosides in serum.

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Frequency, indications, outcomes, and predictive factors of opioid switching in an acute palliative care unit. By using the signal obtained from either reference beam, the vibration of fiber can be measured from the polarization effect. The Escherichia coli chemoreceptor Tsr mediates tactic responses to serine, repellents, and changes in temperature. One hundred eighty-two patients transferred from 37 acute-care hospital ICUs.

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We sought to determine whether putative increases in blood alcohol, produced by accelerated gastric emptying following diet cola consumption, as identified in the laboratory, also appear in a natural setting associated with impaired driving. Gold-loaded polymeric micelles for computed tomography-guided radiation therapy treatment and radiosensitization.

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We introduce inhomogeneity into these networks by assigning each edge a weight that is determined by amino acid pair potentials. In addition to this no activation of Factor IX or prothrombin was observed. Deposition: a voyage of discovery, or just a fishing expedition? Histological analysis indicated that heavy exercise induced leukocyte infiltration, fibrotic connective tissue deposition, and hypercontractures in the diaphragm of KO mice. Heterogeneity and publication bias were assessed for individual outcomes.

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After 20 h those of the co-treated group had also become electron dense and appeared to contain numerous dark dots. Instead, echinoderm TR contains a distinct simple helical region, termed eCR4/5, that is functionally equivalent to the CR4/5 domain. Pro-inflammatory flagellin proteins of prevalent motile commensal bacteria are variably abundant in the intestinal microbiome of elderly humans.

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We included randomised controlled trials comparing music added to standard care during caesarean section under regional anaesthesia to standard care alone. Fifty-one patients with MDD (15 male and 36 female) participated in this study.

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In South Africa, the majority of tuberculosis (TB) patients are co-infected with the human immunodeficiency virus (HIV), and delays in diagnosis and treatment likely exacerbate morbidity and mortality. These results support the functional importance of reinnervation in transplanted hearts.

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Tracheobronchial mucus secretion in vivo and in vitro by epithelial tissues from cystic fibrosis and control subjects. The future development of selective and unselective FGFR inhibitors will rely on a better understanding of the tissue-specific role of FGFR signaling and identification of biomarkers to select those patients who will benefit the most from these drugs. Multivariable long-term monitoring of cerebral and cardiovascular values using a personal computer Firstly, wound-induced depolarizations are not brought about by shunting of the cell resistance in the wound area. Our purpose was to determine whether blockade of inducible or endothelial nitric oxide synthesis prevents maternal vasodilation and blunting of angiotensin II responsiveness in the pregnant rat.

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Radiological protection for space flights is often perceived as a technico-scientific problem. The application of writing exercises and the relevance of stage-matching is discussed in the context of the stage of change model. In spite of adverse social and political circumstances in the Mongolian era, the book contributed to the reconstitution of Persian pharmacy and medicine, serving as a basic reference for the compilation of other drug manuals and scientific works for centuries after its introduction. A general theory is, thus, obtained which provides the different modes of nucleation based on the size of the seed ranging from zero (corresponding to the homogeneous mode of nucleation) to infinity (corresponding to the heterogeneous nucleation on flat surface). Microcalorimetric study of human blood lymphocytes culture at presence of copper, cadmium and prostamax.

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Streptozotocin (another diabetogen) has the same effect as alloxan on adrenal cortex cells. The authors also sought to determine whether there were differences in demographics in these two groups. Toll-like receptor activation and expression in bovine alpha-herpesvirus infections. Optimal approach to sporadic desmoid tumors: from radical surgery to observation.

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To determine the incidence of adverse drug events (ADEs) and assess their severity and preventability. This is the first report to implicate TXNIP in a human disorder of energy metabolism, Type 2 diabetes.

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PCNL procedures were performed according to local clinical guidelines and practices. Dissipative motion of an electron-phonon system in a uniform electric field: An exact solution. These results were correlated with the fatty acid profile of different lipid fractions of plasma and with the activity of enzymes involved in polyunsaturated fatty acids biosynthesis measured in the testicular microsomes of diabetic rats. In vivo treatment with estradiol (E2) led to an increase in the specific activity of thymic creatine kinase (CK) in the female mice, whereas the male thymocytes responded with an increase in CK activity only on treatment with dihydrotestosterone (DHT).

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Therefore, different explanation models for these findings should be explored in future studies. Passive immunisation is an important means of preventing hepatitis A in the most vulnerable populations in the event they are exposed. In total, 113 patients with retinal artery occlusion and 463 patients with retinal vein occlusion were enrolled and matched for age, sex, and the duration of hemodialysis (at a 1:5 ratio) with patients without ocular disorders. To describe the temporal bone histopathology in 2 individuals with XP (XPA and XPD) with neurologic degeneration and to discuss the possible causes of deafness in these patients. A cDNA probe to CPT was developed, and transcriptional activity for CPT was assessed in isolated hepatic nuclei.

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Molecular epidemiology of paramyxoviruses in frugivorous Eidolon helvum bats in Zambia. Lateral column lengthening through the calcaneus, for planovalgus foot deformity, significantly improved the segmental alignment of the foot with respect to radiographic assessment. Increased RIP140 level may be closely associated with inflammation and disorder of lipid and glucose metabolism in diabetic patients.

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Super-resolution imaging with Pontamine Fast Scarlet 4BS enables direct visualization of cellulose orientation and cell connection architecture in onion epidermis cells. Presence of lobules of adipose tissue either focally or diffusely is very rare in the thyroid gland. Although eurythmy therapy (ET) has been used in the context of anthroposophic medicine (AM) for the treatment of, among other conditions, arterial hypertension (AH) for more than 80 years, there are as yet no studies on its effectiveness on disease entity. The validation of a fontanometer based on the strain-gauge principle is described. Five infant deaths were directly attributed to mismanaged forceps.

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Quantification of spermatozoa in the sperm-storage tubules of turkey hens and the relation to sperm numbers in the perivitelline layer of eggs. Size, shape, and orientation of neurons in the left and right hippocampus: investigation of normal asymmetries and alterations in schizophrenia. Progesterone is emerging as an important protective agent against various injuries to the nervous system.

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Pheromones released by females attract and stimulate males in some taxa (insects, crayfish, goldfish, and crucian carp), whereas pheromones released by males attract females in others (round goby, sea lamprey). Addition of asolectin and removal of the detergent by dialysis resulted in reconstitution of NEM-sensitive electrogenic proton transport.

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Findings point to the utility of microarray analyses in identification of pain-, neurotrophin and nerve-related genes in the disc, and point to the importance of future work exploring functional interactions between nerve and disc cells in vitro and in vivo. In all cases, a number of concerns can be raised regarding the reliability of the current assessments, some examples being absence of data audits, use of single-dose and/or non-good laboratory practice studies to determine safety metrics, use of a biased data set and questionable methodology and lack of consistency with precedents and regulatory guidance. A randomized, prospective, controlled study was conducted in the chinchilla animal model. The aim of the study was to investigate the relationships between childhood type 1 diabetes and socioeconomic conditions, which might provide clues to the aetiology of the disease. Infection prevention and control implications include the need for hand hygiene and personal protective equipment to minimize self-contamination and to protect against inoculation of mucosal surfaces and the respiratory tract, and enhanced surface cleaning and disinfection in healthcare settings.

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This study demonstrates that the preservation of the periosteal blood supply alone can result in complete bone-graft survival even when the graft is placed in a poorly vascularized tissue bed. In the present work, we reviewed the progress of astrovirus infections in humans, focusing on the serotypes molecular biological, characteristics of disease, pathogenic mechanism, epidemiology and detection methods, and concluded that there were multiple astroviruses circulating in the world, and several novel astroviruses were discovered in recent years. Administration of GLA-60, a synthetic lipid A-subunit analogue, significantly increased the numbers of macrophages, lymphocytes and polymorphonuclear leukocytes (PMN) in the peritoneal cavity of cyclophosphamide (CY)-treated immunosuppressed mice. The proinflammatory peptide substance P promotes blood-brain barrier breaching by breast cancer cells through changes in microvascular endothelial cell tight junctions.

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Although persistence of rubella virus (RV) in fetal endothelium has been repeatedly suggested as a possible cause of cardiovascular birth defects, evidence of the permissiveness of fetal endothelial cells to RV is lacking. Superconductor-Mott-insulator transition in Bose systems with finite-range interactions. Macrocytosis is also found by ordinary microscopic examination of the blood cells. This ability can also be attributed to baboons being able to recognize specific letters (i.e., shapes) in specific positions in their four-letter words, without reference to letter or bigram frequencies.

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Peripheral nerve entrapment syndromes involve the compression of a short segment of a nerve at a specific site, as a result of the vulnerability of that nerve as it passes through a fibroosseous tunnel or an opening in fibrous or muscular tissue. The identity and predictive potential differed in normotensive women and those who developed hypertension.