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Topamac (Topiramate)

Topamac is an oral drug that is used to prevent the seizures of epilepsy. It is an anti-epileptic or anti-seizure drug. It is used primarily among patients who are not controlled by other anti-epileptic drugs. About 1 in 4 Americans diagnosed with epilepsy has seizures that resist treatment with other anti-epileptic drugs. Topamac also prevents migraine headaches. Seizures are due to the abnormal activity ("firing") of nerves in the brain, and the abnormal activity spreads to smaller or larger portions of the brain. Although Topamac's exact mechanism of action is unknown, scientific studies suggest that it may alter neurotransmitters within the brain. Neurotransmitters are chemicals that nerves manufacture and use to communicate with other nearby nerves. By altering the production or action of the neurotransmitters, Topamac may suppress the abnormal activity of the nerves in the brain that cause the seizures or may prevent the abnormal activity from spreading to other nerves. Other studies suggest that Topamac may suppress the nerves directly (i.e., not by altering neurotransmitters) and make them less likely to fire. The FDA approved Topamac as a tablet in 1997. The sprinkle capsules were approved in October 1998.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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When REHIPs are incubated with TGF-beta before addition of Abeta, the Bcl-xL/Bcl-xS ratio and Bcl-2 levels are increased compared to cells treated with Abeta alone. The Leningrad Pasteur Research Institute of Epidemiology and Microbiology during World War II Alpha1-adrenoceptors of both subtypes in male and female horses had a higher affinity for prazosin than phentolamine, whereas yohimbine did not compete with the radioligand for binding.

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Establishment and characterization of strain KE-24 derived from human colonic cancer Samples were taken daily during the first four weeks and then every two or three days over the following weeks until the end of the experiment. A kinetic scheme with five closed and five open states, in which each closed state could make a direct transition to an open state (two-tiered model) could account for the major features of the single-channel data.

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The application of the biological feedback technique for the treatment of the patients presenting with chronic somatic diseases Detailed observations of larval Drosophila chemotaxis have characterised the relationship between the odour gradient and the runs, head casts and turns made by the animal. Main cardiac surgery procedures performed in Poland in 2014 (according to the National Registry of Cardiac Surgery Procedures - KROK, Warsaw, Poland 2015). To our knowledge, this is the first study to show that a vertebrate modifies the anti-predator strategy of its offspring in response to natural variation in reproductive phenology, which highlights the need to consider phenology in studies of life-history evolution. Similar survival benefits of a good response and stable disease to platinum-based chemotherapy in non-small cell lung cancer.

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Role of short distance behavior in off-shell open-string field theory. It was the aim of the study to investigate a possible association between Hcy plasma levels in young patients with the extent of CAD and the history of myocardial infarction (MI). The demographics and costs of inpatient vesicoureteral reflux management in the USA. They also avoid the introduction of an additional stent layer in the context of in-stent restenosis.

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Unusual Spontaneous Mandibular Regeneration of a Large Defect Followed by Orthodontics, Alveolar Distraction, and Dental Implant Rehabilitation: A 10-Year Follow-Up. Staphylococcus aureus and E coli can cause endophthalmitis immediately on the first day post-operatively. Celite or diatomaceous earth, or immobilisation on a functionalised silica surface, e.g.

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Also, there is some evidence that profit-seeking hospitals achieve some of their goals by controlling costs, and that diagnostically related groups (DRG)-based Medicare services are effective in getting hospitals to control costs. Outcome after modified Putti-Platt procedure for recurrent traumatic anterior shoulder dislocations.

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Sepsis is a complication that can present during the neonatal period. The clear and simple i-FCIQMC wave functions obtained for these systems are then compared and investigated to demonstrate the dynamic identification of the dominant determinants contributing to significant static correlation. There is no variation of PB1-F2 genes of Novel H1N1 virus in Guangzhou compared with the worldwide strains. During the 7th month, the outer segment increased in length, the cell increased in size and the cell organelles increased in number.

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Analysis of the function and state of the cardiovascular system in an experiment using a mathematical model How home hospice care facilitates patient and family engagement. These patients should be followed up for a prolonged time to determine whether they develop conditions associated with insulin resistance. We purified from chlamydial elementary bodies a genus-specific 57-kD protein that elicited an ocular hypersensitivity response when placed topically onto the conjunctiva of ocular immune guinea pigs. Three-dimensional visualization of the route of protein import: the role of nuclear pore complex substructures.

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Asymmetric synthesis of 2-substituted oxetan-3-ones via metalated SAMP/RAMP hydrazones. The field of retinal imaging through a Morcher poly(methyl methacrylate) (PMMA) black IOL was determined in a purpose-built adult schematic model eye with the HRA2 Spectralis confocal scanning laser ophthalmoscope using standard imaging, Staurenghi retina lens-assisted imaging, and ultra-widefield noncontact imaging. The studies provided development of an extraction polarimetric method for quantitative determination of Ac-D-PhG.

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These histopathologically-recognized morphological variants respond differently to treatment and have distinct prognoses. The stable degradation product for prostacyclin, 6-keto-PGF1 alpha was not altered by addition of these agents.

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Fast-track surgery combined with laparoscopy in radical gastrectomy for gastric cancer can accelerate postoperative rehabilitation by promoting postoperative bowel function recovery, and decreasing postoperative hospital stay and complication rate. the resorcinol adhesive, related with the necrosis, cartilaginous degeneration and detachment of the fragment osteochondral lives frequently that the metallic synthesis. Among 10 suggested indicators of water security, 6 were promoted: per-capita renewable water, accessibility of running water, waterborne diseases, drinking-water-related contaminants, authorized water quality assurance and water safety plans.

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Theoretical explanation of zero-field splitting and its pressure, stress, and temperature dependence in NiSiF6 Biological system responses to zearalenone mycotoxin exposure by integrated metabolomic studies. The results presented herein demonstrate the possibility of combining a temperature-responsive brush with polyelectrolyte multilayers without quenching the responsive behavior, even though significant interpolyelectrolyte interactions are present. We show that our self-similar recycling model applied to prothrombin assays reproduces the empirical equations for the International Normalized Ratio calibration (INR), as well as the Watala, Golanski, and Kardas relation (WGK) for the dependence of the INR on the concentrations of coagulation factors.

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Sixty-two patients who underwent pancreatic head resection with pancreatojejunostomy. The phase image: its relationship to patterns of contraction and conduction. Leveraging the differentially expressed miRNAs identified in our previous dataset, we constructed a miRNA-TF-gene network relevant to SZ, including an EGR1-miR-124-3p-SKIL feed-forward loop.

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Sleep problems appear to differentially affect racial minorities and people of lower socioeconomic status (SES). Shared decision-making, control preferences and psychological well-being in patients with RPE65 deficiency awaiting experimental gene therapy. Human H1N1 and H3N2 viruses replicated efficiently in PTECs and PBECs, and viruses containing cleaved HA were released from infected cells.

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Houston hospital merges health promotion, haute cuisine in unique restaurant venture. Hyperbaric oxygenation for the treatment of acute cerebral edema.

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We found that phosphocreatine recovery after exercise, a measure of skeletal muscle mitochondrial function in vivo, was significantly slowed in patients with INSR mutations compared with that in healthy age-, fitness-, and BMI-matched controls. An optimized method applied to whole cells can productively enrich specific phage Fab in mixtures with large excesses of non-specific phage Fab over several rounds of panning. We hypothesize that grafted EGF-responsive stem cells and their progeny are not competent to project axons into distant target sites unless exposed to specific neurotrophic factors. Compensatory fuzzy neural networks-based intelligent detection of abnormal neonatal cerebral Doppler ultrasound waveforms. Steroid-resistant nephrotic syndrome (SRNS) is a common problem but difficult to treat for pediatric nephrologists.

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Twenty-nine candidate genes within loci previously reported to be linked to HbF level (6q22.3-q23.2, 8q11-q12 and Xp22.2-p22.3), involved in metabolism of HU and related to erythroid progenitor proliferation were studied in 137 sickle cell anemia patients treated with HU. The groups were compared in terms of the demographic and peri-operative parameters.

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Dynamic changes in the heart beat frequency of rabbits to auditory and nociceptive signals against the background of neuroleptic action Oral leukoplakia, a heterogeneous group of lesions, demonstrates a varying degree of risk for cancer progression. Insights into the structure and behavior of tropoelastin have translated into increasingly sophisticated elastin-like biomaterials, evolving from classically manufactured hydrogels and fibers to new forms, stabilized in the absence of incorporated cross-linkers. Taken together, these findings suggest that early social experience and experience-related long-term changes in serotonergic function may play a role in the intergenerational transmission of maternal rejection from mothers to daughters. Plasma concentrations of the two compounds were measured simultaneously by reversed-phase h.p.l.c.

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Effect of processing parameters for electrocatalytic properties of SnO(2) thin film matrix for uric acid biosensor. This study analyzed 288 aircraft incidents involving human error from an Australasian military organization occurring between 2001 and 2008. However, there are no studies available that analyzed the influence of ss interaction on estimation of genetic parameters in horses.

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Although overall ED volume continues to increase, Massachusetts health reform was associated with a small but statistically significant decrease in the rate of low-severity visits for those populations most affected by health reform compared with a comparison population of individuals less likely to be affected by the reform. Management of hyperbilirubinemia of the term newborn in maternity wards Our results showed that both optical and NMR approaches have acceptable sensitivity and accuracy for dose determination with NIPAM gel. The improvements were primarily irrespective of surface topography. Death-discordant twins--a new method to evaluate genetic factors in chronic diseases.

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Very early tracheal extubation without predetermined criteria in a liver transplant recipient population. Changes in neutrophil precursor populations in the bone marrow and their alkaline phosphatase reactivity following an inflammatory stimulus were studied in the rat using an osmiophilic method. There have been some indications that other types of hemopoietic cells may be influenced by the mutation and development of the humoral immune system is unusually dependent on the presence tetracycline eye ointment children of T lymphocytes. Evidence for low intrinsic surface-recombination velocity on p-type InP. In three subjects, the same measurements were made during spontaneous cough.

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Despite the existence of an effective measles vaccine, resurgence in measles cases in the USA and across Europe has occurred, including in individuals vaccinated with two levofloxacin injection phobias doses of the vaccine. To investigate the safety and effectiveness of a novel endovascular approach for therapeutic cell delivery using a balloon occlusion catheter in a large animal model of liver fibrosis.

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Fifty-nine revisions that were done for aseptic acetabular loosening after 6,128 total hip arthroplasties for degenerative arthritis or traumatic arthritis were studied. Canaloplasty as a new interventional surgery is compared to trabeculectomy (TE) kailasa temple photos in india by means of a cost and effort analysis. This inflammation may be the result of non-immunologically triggered processes as well as of immunological reactions. Search for supersymmetric particles in hadron-hadron collisions.

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Determination of weathering rate of the Morro do Ferro Th-REEs deposit, Brazil using refluxon 30 mg kapszula film U-isotope method. To demonstrate the abscopal mutagenic effect of low-energy-ion irradiation in dormant plant seeds, and its dependence on the targeted portion of seeds. Experience report on the use of a new medium spectrum antibiotic in pediatrics

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Parents United of Oregon: a natural history of a self-help group for sexually abusive families. The patient had no involvement of the myometrium, cervix, or extra-uterine sites. Failure of IIABO can be explained by valvirex y alcohol the presence of extensive anastomoses in the pelvic vasculature. Quantitative Measurements of Size-Dependent Magnetoelectric Coupling in Fe3O4 Nanoparticles.

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Chemical composition, antimicrobial, antioxidant and cytotoxic activity of essential oils of Plectranthus cylindraceus and Meriandra benghalensis from Yemen. The potential of new spatial technology applications utilising emerging satellite information, as they hold promise to further enhance infectious risk mapping and disease prediction, are outlined. Targeted screening for childhood lead exposure in a low prevalence area--Salt Lake County, Utah, 1995-1996. Obesity may contribute independently of smoking habits to chronic airflow carvedilol 12.5 mg indicaciones tonval 40 limitation in men. The roles of PPARbeta/delta in metabolic regulations remained unclear until recently.

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Laparoscopic approach to fibroid torsion presenting as an acute abdomen in pregnancy. Linear allegron nortriptyline hydrochloride abuse regression was used to examine the association between sodium excretion, as a measure of salt consumption, and subsequent changes in BW, WC, BF and FFM, and further evaluated by restricted cubic splines. Furthermore, Te2 inactivation prevents changes in the valence of such information.